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NEONATAL SOCIETY ABSTRACTS

Retinopathy of prematurity in infants <30 weeks' gestation in NSW and the ACT from 1992-2002

Presented at the Neonatal Society 2004 Summer Meeting (programme).

Todd DA, Wright A, Byth K, Smith J and the NICUS Network

NICU Westmead Hospital, Westmead, Sydney, NSW Australia, 2145 and the NSW and ACT Neonatal Intensive Care Units Network

Introduction: Retinopathy of Prematurity (ROP) still remains one of the main morbidities for the preterm infant. We showed that in NSW from 1986-92 there was an increased incidence of ROP, but more recent data suggests that over the last few years the incidence has decreased (1,2).

Aims: To study the incidence, severity and treatment of ROP in NSW & the ACT from 1992-2002.

Methods & materials: Prospective data from the NICUS Network Data Collection was reviewed over an 11 year period to study ROP in infants <30 weeks' gestation. The 11 year period was divided into 4 epoch's to review the trend (Jan 92-Dec 94, Jan 95-Dec 97, Jan 98-Jun 00 & Jul 00-Dec 02). The infant groups were divided into those =24 weeks' those 25-26 weeks' and those 27-29 weeks' gestation. The data was analysed using SPSS for Windows Version 10.

Results: In the infants =24 weeks' there was no change in survival but the rate of severe ROP (Stage = 3) after initially decreasing, has significantly increased to 54%. The percentage of infants treated has significantly increased to 33%. In the infants 25-26 weeks' there was a significant increase in survival and the rate of severe ROP has significantly decreased, but the percentage of infants treated has increased over the 4 epoch's. In the infants 27-29 weeks', there was a significant increase in survival and the rate of severe ROP and those treated has decreased. There was little change in the percentage of infants examined for ROP over the 11 years.


* Significantly increased trend over time p<0.05, ** significantly increased trend over time p<0.02, *** significantly decreased trend over time p<0.05, # significantly different to 92-94 Epoch p<0.02, ## significantly different to 92-94 Epoch p<0.05.

Conclusion: In NSW and the ACT, the incidence of severe ROP and those treated has significantly increased in infants =24 weeks' gestation. This was not the case in the infants with longer gestational ages. A greater awareness and willingness to treat may be the reason for these changes.

References
1. Todd DA. et al. ROP in infants <29 weeks' gestation in NSW from 1986-92 J Paediatr. Child Health. 1998; 34: 32-36.
2. Public Health Division. New South Wales Mothers and Babies 2000: NSW Health Bulletin Supplement. 2001; 12: No. S-3 page 66.

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